Random effects meta-analysis of all studies combined (pooled effects, all stages). Treatments with ≤3 studies with distinct authors or with <50 control events are shown in grey. Pooled results across all stages and outcomes depend on the distribution of stages and outcomes tested – for example late stage treatment may be less effective and if the majority of studies are late stage this may obscure the efficacy of early treatment. Please see the specific stage and outcome analyses. Protocols typically combine multiple treatments which may be complementary and synergistic, and the SOC in studies often includes other treatments.
Random effects meta-analysis of
all studies combined (pooled effects, all stages). Treatments with ≤3
studies with distinct authors or with
<50 control events are shown in grey.
Pooled results across all stages and outcomes depend on the distribution of
stages and outcomes tested – for example late stage treatment may be less
effective and if the majority of studies are late stage this may obscure the
efficacy of early treatment. Please see the specific stage and outcome
analyses.
Protocols typically combine multiple treatments which may be complementary and
synergistic, and the SOC in studies often includes other treatments.
Random effects meta-analysis of
early treatment studies (pooled effects). Treatments with ≤3
studies with distinct authors or with
<50 control events are shown in grey.
Pooled results across all outcomes are affected by the distribution of
outcomes tested, please see detail pages for specific outcome analysis.
Protocols typically combine multiple treatments which may be complementary and
synergistic, and the SOC in studies often includes other treatments.
Random effects meta-analysis of
all mortality results (all stages). Treatments with ≤3
studies with distinct authors or with
<25 control events are shown in grey.
Pooled results across all stages depend on the distribution of stages tested –
for example late stage treatment may be less effective and if the majority of
studies are late stage this may obscure the efficacy of early treatment. Please
see the specific stage analyses.
Protocols typically combine multiple treatments which may be complementary and
synergistic, and the SOC in studies often includes other treatments.
Random effects meta-analysis of
early treatment mortality results. Treatments with ≤3
studies with distinct authors or with
<25 control events are shown in grey.
Protocols typically combine multiple treatments which may be complementary and
synergistic, and the SOC in studies often includes other treatments.
